As complex as this whole operation sounds, it's not that difficult. That said, I've gone through this process many times now and I still miss things, usually something as silly as a typo. Thin-client computing does bring some interesting challenges into the picture, however, especially when dealing with devices connected to the thin clients themselves. Add to that the fact that a thin-client device can be anything from a vintage PC with any number of different network or video cards or any of several different types of hardware, and it's possible to run into the odd snag.
I'm going to talk about thin clients in a moment, but for now, I want to tell you about a great resource, the #ltsp IRC channel on irc.freenode.net. Many people who frequent this channel are either developers on the project or just plain enthusiastic users. If you run into problems, this is always a great place to ask questions.