#2: Connect with People in Your Industry
Use search.twitter.com and Twellow.com to connect with people who are possible clients. Search for keywords they are likely to use, especially in their bios. If you are an accountant who specializes in restaurants, do a search for restaurant owners, as well as other people who are likely to work with restaurant owners, such as suppliers and marketers.
Set up a list for these connections on Twitter.com or on TweetDeck. Talk to these people about the things they're talking about. Respond to them, participate in their discussions, and retweet their interesting tweets.
As you connect with these people, connect with them on other networks too, such as LinkedIn and their blogs. Find ways to connect with them offline, too, if at all possible. If you live in a larger city with a lot of people in that industry, meet them for coffee or lunch. This deepens the Twitter relationship, and you'll be more likely to pay attention to each other.