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This new case study focuses on the macro risks associated with relying on global supply chains. It addresses large events including floods, earthquakes, hurricanes, fires, and tornadoes; manmade disasters such as wars and economic crises; and technical disasters ranging from transport accidents and explosions to fires, gas leaks, and industrial accidents. Coverage includes risk classification; strategic, tactical, and operational issues; and a complete supply chain resilience model designed to help both students and practitioners effectively integrate macro risks into planning. Authors: Matthias Klumpp and Hella Abidi; both from FOM University of Applied Sciences.