Antibiotic Resistance: Understanding and Responding to an Emerging Crisis
- By Karl S. Drlica, David S. Perlin
- Published Feb 9, 2011 by FT Press. Part of the FT Press Science series.
- Copyright 2011
- Dimensions: 7" x 10"
- Pages: 288
- Edition: 1st
- Book
- ISBN-10: 0-13-138773-1
- ISBN-13: 978-0-13-138773-7
Register your product to gain access to bonus material or receive a coupon.
Product Author Bios
Karl Drlica is a member of the Public Health Research Institute, and professor of Microbiology & Molecular Genetics at the New Jersey Medical School in Newark. Drlica is author of Understanding DNA and Gene Cloning: A Guide for the Curious and DoubleEdged Sword: The Promises and Risks of the Genetic Revolution.
David S. Perlin directs the Public Health Research Institute and served as professor of Microbiology & Molecular Genetics at the New Jersey Medical School in Newark. He is also co-author of The Complete Idiot's Guide to Dangerous Diseases & Epidemics.
Authored by two leading investigators, this book presents a thorough and authoritative overview of this multifaceted field of science. Pathogenic bacteria have been evolving and spreading resistance to diverse classes of antibiotics. As a result, we risk losing our ability to control and treat infectious diseases. Understanding antibiotic resistance, therefore, is becoming increasingly essential for a broad audience of healthcare professionals, biomedical and public health researchers, students, and policymakers. The authors answer questions such as: What is resistance? How does it emerge? How do common human activities contribute to resistance? What can we do about it? How can we strengthen our “first lines of defense” against resistance? Are there better ways to discover new antibiotics? What unique issues are associated with MRSA and viral influenza? In addition to defining and evaluating one of the most important emerging threats to public health, the authors explain what can be done to minimize risks to public health, and to preserve and extend the effectiveness of existing and new antibiotics.
|
8 of 8 people found the following review helpful
readable for a layman. too fundamental for experts,
This review is from: Antibiotic Resistance: Understanding and Responding to an Emerging Crisis (FT Press Science) (Hardcover)
Customer review from the Amazon Vine™ Program (What's this?)
Having finished the book in one sitting, I flipped back to the preface in search of what its targeted audience is. It was "initially drafted to supplement studies of infectious disease" and the authors later "aim to make the principles of antibiotic use and effectiveness available to a large audience: farmers, hospital administrators.....and especially individual users."The book's content and style of writing serves well for the above targeted audience. The book is suitable for use at a high school or college freshman year level as a supplement. Interesting historical facts and social ramifications interspersed throughout the book. The book is light on the academic or theoretical side of it, probably intentionally so. It touches on biological mechanisms just enough to make a layman understand what they want to tell next, nothing more. Nonetheless, this book is a laudable attempt to educate the public about the subject.
7 of 8 people found the following review helpful
Trying to Outwit Pathogens Isn't Easy, By
This review is from: Antibiotic Resistance: Understanding and Responding to an Emerging Crisis (FT Press Science) (Hardcover)
Customer review from the Amazon Vine™ Program (What's this?)
"...One of the Klebsiella pneumoniae isolates contained 2 integrons and was resistant to 8 antibiotics. Nucleotide sequence analysis of some of the integrons revealed a complex history involving insertion into a transposon and homologous recombination between transposons."What's it all mean? I'm not sure, and unfortunately too much of the information in this timely, important book entered my brain like figures shrouded in smoke, visible yet not clearly identifiable, requiring the time and effort to blow away the smoke to come face to face with something unrecognizable anyway. Much of my denseness can be blamed on this English major's non-science background , and some may be attributed to the complexity of the subject matter itself. The authors establish early that antibiotic resistance is an emerging crisis, one that needs to be addressed immediately, correctly, and ubiquitously to avoid future calamity and a regression in health care to the days before... Read more
3 of 3 people found the following review helpful
Antibiotic Use: Cause and Effect, By
This review is from: Antibiotic Resistance: Understanding and Responding to an Emerging Crisis (FT Press Science) (Hardcover)
Customer review from the Amazon Vine™ Program (What's this?)
The authors outline and explain a problem that is not new but is starting to be brought into the public light. This book is written for people who use antibiotics and is written at an introductory yet clear level. The paramedics, farmers, hospital administrators and especially the public at large should read this book. If you do not have a background in basic biology the authors have included two appendix that give the basic background required to understand the rest of the text and I would recommend starting there.The book is well presented on how the medical and agricultural use of antibiotics and their misuse has lead to pathogens mutating and becoming antibiotic resistance. And at present dosage and actually overuse of antibiotics will lead to a pathogen that will cause a pandemic. When is not discussed but when you read that rate at which the resistance strain mutate and spread it seems that this should be a subject of high priority. Yet pharmaceutical companies have... Read more |
Table of Contents
Preface xv
Chapter 1 Introduction to the Resistance Problem 1
Chapter 2 Working with Pathogens 17
Chapter 3 A Survey of Antibiotics 31
Chapter 4 Dosing to Cure 55
Chapter 5 Emergence of Resistance 73
Chapter 6 Movement of Resistance Genes Among Pathogens 91
Chapter 7 Transmission of Resistant Disease 105
Chapter 8 Surveillance 125
Chapter 9 Making New Antibiotics 139
Chapter 10 Restricting Antibiotic Use and Optimizing Dosing 149
Chapter 11 Influenza and Antibiotic Resistance 167
Chapter 12 Avoiding Resistant Pathogens 177
Afterword A Course of Action 203
Appendix A Molecules of Life 207
Appendix B Microbial Life Forms 221
Glossary 227
Literature Cited 233
Index 251
Sample Pages
Download the sample pages (includes Chapter 1 and Index)
This book includes free shipping!
This book includes free shipping!
eBook (Watermarked)
$49.99
$39.99
Includes EPUB, MOBI, and PDF
About eBook Formats
This eBook includes the following formats, accessible from your Account page after purchase:
EPUBThe open industry format known for its reflowable content and usability on supported mobile devices.
MOBIThe eBook format compatible with the Amazon Kindle and Amazon Kindle applications.
PDFThe popular standard, used most often with the free Adobe® Reader® software.
This eBook requires no passwords or activation to read. We customize your eBook by discretely watermarking it with your name, making it uniquely yours.
- Request an Instructor or Media review copy.
- Corporate, Academic, and Employee Purchases
- International Buying Options
Get access to thousands of books and training videos about technology, professional development and digital media from more than 40 leading publishers, including Addison-Wesley, Prentice Hall, Cisco Press, IBM Press, O'Reilly Media, Wrox, Apress, and many more. If you continue your subscription after your 30-day trial, you can receive 30% off a monthly subscription to the Safari Library for up to 12 months. That's a total savings of $199.
