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This new case study offers an insider view of Stanford Blood Center’s crucial initiative for improving processes associated with the supply of platelets, crucial blood products with a short five-day shelf-life and volatile demand patterns. Walking through the entire platelet supply chain--collection, processing, testing, delivery, and more--it helps readers assess significant process flaws that could have led to the loss of donors and life-threatening platelet shortages. Throughout, it focuses on realistic issues and challenges, offering exceptional value to both students and practitioners. Authors: Yenho Thomas Chung, LG CNS Entrue Consulting Partners; Feryal Erhun, Stanford University; Tim Kraft, University of Virginia.