PrintNumber ErrorLocation Error Correction DateAdded
2 iv Second Printing November 2009 Third Printing TBD 3/29/2011
2 v He oversaw the final sale of the company in 1999 to Johnson & Johnson for nearly $5 billion, after it had regained its lofty stock price of around $60 per share. He oversaw the final sale of the company in 1999 to Johnson & Johnson for about $5 billion, after it had regained its lofty stock price of around $60 per share. 3/29/2011
2 4 In 1993, researcher Cynthia Kenyon was able to double the roundworm’s life span by making a single mutation in the daf-2 gene, just one of the 19,000 genes in this nematode’s genome. Such mutated nematodes not only live longer, but also live healthier. This single mutation in daf-2 has far-reaching effects on the worm’s metabolism, its response to environmental stress, its ability to fight infection, and its control of damage by free radicals.5 The end result of these cellular effects is a remarkable slowdown in aging.6 Since the discovery of daf-2, scientists have located other longevity genes in yeast, fruit flies, mice, and rats. In 1993, researcher Cynthia Kenyon was able to double the roundworm’s life span by making a single mutation in the DAF-2 gene, just one of the 19,000 genes in this nematode’s genome. Such mutated nematodes not only live longer, but also live healthier. This single mutation in DAF-2 has far-reaching effects on the worm’s metabolism, its response to environmental stress, its ability to fight infection, and its control of damage by free radicals.5 The end result of these cellular effects is a remarkable slowdown in aging.6 Since the discovery of DAF-2, scientists have located other longevity genes in yeast, fruit flies, mice, and rats. 3/29/2011
2 5 In yeast and worms, the SIR2 gene seems to influence longevity. Researchers have identified a similar gene in flies, mice, and humans.n In yeast the longevity gene SIR2 seems to be involved. Researchers have identified a similar gene in worms, flies, mice, and humans (SIRT1).1 3/29/2011
2 5 Scientists have cloned many therapeutically important proteins in the laboratory, including insulin and human growth hormones, to replace our own hormones. Eventually, this will lead to tissue regeneration and perhaps the replacement of entire organs. Eventually, this will lead to tissue regeneration and perhaps the replacement of entire organs. In addition, scientists have cloned many therapeutically important proteins in the laboratory, including insulin and human growth hormones, to replace our own cells. 3/29/2011
2 34 9Nucleotides in DNA contain a deoxyribose sugar, a phosphate group, and one of four different nitrogen-containing chemical bases: adenine (A), thymine (T), guanine (G), and cytosine (C) which show up in pairs of AT and CG (refer to Figure 2.1). 9Nucleotides in DNA contain a deoxyribose sugar, a phosphate group, and one of four different nitrogen-containing chemical bases: adenine (A), thymine (T), guanine (G), and cytosine (C) which show up in pairs of AT and CG (refer to Figure 2.2). 3/29/2011
2 50 This final section first discusses stem cells, which are undifferentiated (immature) cells found in the embryo as well as in of adult tissues. Stem cells have tremendous therapeutic promise for curing diseases such as diabetes, heart disease, and Parkinson’s disease. This final section first discusses stem cells, which are undifferentiated (immature) cells found in the embryo as well as in adult tissues. Stem cells have tremendous therapeutic promise for curing diseases such as diabetes, heart disease, and Parkinson’s disease. 3/29/2011
2 67 This new computing power will fuel a new breed of implantable sensors that transmit large quantities of medical data about consumers in their natural setting. This new computing power will fuel a new breed of implantable sensors that transmit large quantities of medical data about patients in their natural setting. 3/29/2011
2 122 As healthcare systems around the globe evolve, they will likely redefine which of these criteria to weigh more, which will impact the type of technologies that will succeed or fail. As healthcare systems around the globe evolve, they will likely redefine which of these criteria to weigh more, and which will impact the type of technologies that will succeed or fail. 3/29/2011
2 110 Replace map with the AIDS map. Map replaced. 4/6/2011
2 121 Remove subscript on “RNAi” Corrected Subscript. 4/6/2011